What is polymyalgia rheumatica?
It is an inflammatory condition, with the characteristic features of serious muscle and joint ache and stiffness at different part of the body.
To date, the causes of polymyalgia rheumatica is still unknown. It could be genetic or environmental factor.
The risk factors includes female , age over 60, European people and those who have giant cell arteritis.
Nonetheless, polymyalgia rheumatica is closely related to giant cell arteritis, which share a lot in common, that sometimes, we may even considered it as one.
What are the signs and symptoms ?
The characteristic feature of this condition is severe muscle pain and stiffness at the body parts such as the shoulders (the early sign), neck, lower back , buttocks and thighs.
There are also other non-specific symptoms associated with the muscle pain and stiffness such as
- headache
-fever
-night sweats
- tiredness , fatigue
-loss of appetite
- affected mood - depressed
- mild anemia
For most of the cases, the patient experience a sudden and rapid development of the symptoms. Sometimes, some may experience a gradual development of the symptoms over time. In common, the symptoms get worse in the morning, that can last for as long as 45 minutes.
As a result of the disease, you could suffer from doing daily activities, which could be as simple as standing up from a chair or dressing up yourself.
How do I know if I have polymyalgia rheumatica ?
You need to see a doctor. If you have a sudden unknown pain which limits your movement or disturb your sleep. The signs and symptoms of this disease could be very similar to other muscular diseases such rheumatoid arthritis or osteoarthritis.
The doctor will then carry out a few tests (eg. CRP, FBC, LFTs,) to help with the diagnosis in addition to physical examination and patient's medical history. Then, the doctor will try to rule out other possibilities before making a proper diagnosis as polymyalgia rheumatica
What is the treatment plan?
TO reduce or ease the muscle pain, corticosteroid is usually the option such as prednisone.
High doses of prednisone are given in the beginning to dampen down the "flare-up" . Then tapering off the prednisone SLOWLY to dose that the symptoms are controlled. Therefore, this require frequent meet-up with the doctor to adjust the dosage.
Usually, patient will respond quickly to corticosteroid treatment. However, recurrence or relapse of the symptoms could occur once the prednisone is tapered off.
Therefore, usually the doctor will taper off the doses slowly , for instance every two weeks , until to a level that the symptoms are manageable. And, the treatment may then continue for one to two years to prevent the relapse. Other co-morbidities need to be taken into account as well.
In term of this disease, mostly the patient have to take corticosteroid for quite a long period of time, ranging from two years up to ten years ( or even lifetime) , depending on patient factor and disease severity.
Nonetheless, long term corticosteroid treatment incur side effects which could be significant:
- moon face
- cataract
- weight gain (obesity) '
- thinning of the skin
- osteoporosis ( loss of bone density) [doctor may prescribe vitamin D3]
- hyperglycaemia ( increase risk of diabetes) [need to assess blood glucose level periodically)
-increased blood pressure
NOTE: prednisone treatment should NOT be stopped abruptly.
Apart form prednisone, some other pain killers could be added to maintain or control the symptoms.
If patient seek for extra help in the pharmacy, OTC pain killer such as ibuprofen, naproxen could be recommended.
What advice could we give to the patient ?
- The corticosteroid treatment (prednisone) should be taken in the morning, with food.
- If the patient is diabetic, need to ask them to monitor their blood glucose level.
- Exercise + healthy diet advice (especially those on corticosteroid treatment)
- Do not overstressed the body - have enough rest
- Patient can seek alternative treatment such as acupuncture, homeopathy , massage etc.
References
1. https://www.southerncross.co.nz/group/medical-library/polymyalgia-rheumatica
2. http://www.mayoclinic.org/diseases-conditions/polymyalgia-rheumatica/basics/definition/con-20023162
3. http://www.bpac.org.nz/BPJ/2013/June/polymyalgia-rheumatica.aspx
































